Association of platelet glycoprotein Ia C807T polymorphism with ischemic stroke risk in young and elderly populations in Uzbekistan: A case- control study [2026] - 361KB
by Adkham Yusupov, Dilshod Tolibov, Nargiza Qarshiboyeva
Background: Ischemic stroke remains a significant health concern, with a growing incidence among younger populations. While traditional risk factors such as hypertension and smoking are well- document...

Impact of cumulative exposure and variations of small dense low-density lipoprotein cholesterol on the risk of incident cardiovascular diseases or stroke among middle-aged and old adults: Insights from CHARLS [2026] - 838KB
by Genshan Gao, Xinduo Lin, Yao Liu, Shuqing Meng, Yue Xu, Nannuan Liu
Objection: This study aims to investigate the associations of cumulative small dense low-density lipoprotein cholesterol (sdLDL-C) and changes with cardiovascular disease (CVD) or stroke risk in middl...

Predictive value of plasma sLRP1 for three-month clinical outcome in acute ischemic stroke and its potential pathophysiological mechanisms: A retrospective and observational study [2026] - 876KB
by Tingting Li, Peiyi Wang, Guo Hong, Zhongwen Zhang
Background & Objective: Acute ischemic stroke (AIS) remains a leading global cause of mortality and disability; thus, accurate early prognosis is critical for guiding personalized management. Soluble ...

Associations between hematological inflammatory markers, infarct volume, and stroke severity in patients with obstructive sleep apnea and anterior circulation non-large artery occlusion [2026] - 471KB
by Li Zhang, Jun-Qiang Bao, Yan-Ying Zhao, Di Wu, Xiao-Yun Liu
Background: Neuroinflammatory processes are recognized as critical contributors to the pathophysiology of acute ischemic stroke (AIS). Hematological inflammatory markers have demonstrated a strong ass...

The effect of carotid artery geometric measurements and degree of stenosis on infarct volume and in- hospital mortality in patients with middle cerebral artery infarction [2026] - 740KB
by Muzaffer Güneş, Oruç Şahin
Background & Objective: Atherosclerosis of the internal carotid artery (ICA) is a major cause of middle cerebral artery (MCA) infarction. This study aimed to investigate the relationship between carot...

Ticagrelor plus aspirin vs clopidogrel plus aspirin in mild non-cardioembolic ischemic stroke: A randomized, controlled, active comparator arm, outcome assessor blind, feasibility study [2026] - 567KB
by Nasim Tabrizi, Razieh Daz, Athena Sharifi-Razavi
Background: The risk of recurrence after a transient ischemic attack (TIA) or minor stroke is high especially within three months after the first event. The aim of the present study was to assess the ...

Clinical efficacy and safety evaluation of intravenous thrombolysis combined with carotid artery stenting in the treatment of acute cerebral infarction [2026] - 726KB
by Lei Lei, Jin Fan, Zhijie Lu, Tao Huang, Xin Xie, Xi Li, Yao Huang
Objective: To evaluate the clinical efficacy and safety of intravenous thrombolysis (IVrtPA) combined with carotid artery stenting (CAS) in the treatment of acute cerebral infarction (ACI). Methods: W...

Risks for early neurological deterioration after thrombolytic therapy in patients with acute ischemic stroke [2026] - 515KB
by Zhilan Zhang, Guoshuai Yang, Yanhui Zhou, Dan Hou, Yujie Hu, Jiangshan Zhang
Background: Early neurological deterioration (END) is a common complication following intravenous thrombolysis in acute ischemic stroke (AIS). This study aimed to identify factors associated with END ...

Interaction analysis of CONUT score and NLR in predicting functional outcomes after mechanical thrombectomy [2026] - 1,714KB
by Xin Nie, Sheng-Yang Zhou, Le Yao, Meng-Jie Fan, Chao-Sheng Li
Background: This study investigates the prognostic value of the Controlling Nutritional Status (CONUT) score and its relationship with systemic inflammation, measured by the Neutrophil-to- Lymphocyte ...

Hospital Frailty Risk Score (HFRS) in ischemic stroke [2026] - 485KB
by Sher Yin Tan, Bharathi Balasundaram, Thevapriya Selvaratnam, Aileen Lim, Han Leong Goh, Lin Zou, Si Xian Ho, Yunfeng Liang, Andy Ta, Barbara H Rosario
Background & Objective: Frailty results from an age-associated decline in physiological reserve and function and is prevalent in older adults. In this retrospective cohort study, we aimed to validate ...