Association between erythrocyte and platelet related parameters with the initial severity of acute ischemic stroke

Authors

  • Chen Chen
  • Weichao Zhu
  • Tianshuo Sun
  • Haixu Zhao
  • Hui Liu
  • Cui Zhang
  • Mengyuan Hao
  • Qian Liang
  • Guodong Tian
  • Donglai Jing
  • Kangbo Li North China University of Science and Technology

DOI:

https://doi.org/10.54029/2025yhj

Keywords:

acute ischemic stroke, erythrocyte and platelet related parameters, modified Rankin Scale

Abstract

Background & Objective: The purpose of the present study was to evaluate the association between erythrocyte and platelet related parameters with the initial severity of acute ischemic stroke (AIS).

Methods: This observational study included 113 patients with AIS in the 4th Department of Internal Medicine, Xiong’an New District Rongcheng People’s Hospital. Erythrocyte and platelet related parameters including red blood cell distribution width (RDW), hematocrit value (HCT), platelet volume distribution width (PDW), and plateletcrit (PCT) were measured for all patients. In addition, modified Rankin Scale (mRS) was performed to assess the initial severity of AIS for all patients. Ordinal logistic regression analysis was used to investigate the association between the erythrocyte and platelet related parameters with mRS.

Results: RDW was positively and significantly associated with mRS (Estimate = 0.532, P = 0.025, 95% CI: 0.067, 0.997) in patients with AIS.

Conclusion: RDW is associated with the initial severity of AIS.

Published

2025-10-06

Issue

Vol. 30 No. 3 (2025)

Section

Original Article