Gut to brain: Celiac disease beyond the Intestine — A neurological case series [2026] - 847KB
by Bhawna Sharma, Shubham Agrawal, Swati Garg, Ashish Gupta
Celiac disease (CD) is an autoimmune disorder triggered by gluten ingestion in genetically predisposed individuals, leading to small intestinal damage and malabsorption. While gastrointestinal symptom...

Inflammatory pathways in cerebral ischemia- reperfusion injury: Focus on the NLRP3 inflammasome [2026] - 2,381KB
by Yan Cheng, Ji Wang, Zhengjie Fan, Man He, Jing Chen, Yiwei Xu
Cerebral ischemia-reperfusion injury (CIRI) is a severe neurological disorder characterized by exacerbated brain tissue damage and deteriorated neurological function following the restoration of blood...

PERK signalling in neurodegenerative diseases: From ER stress to mitochondrial dysfunction and therapeutic opportunities [2026] - 747KB
by Tao Xu, Shengwei Jing, Jing Wu
The PERK (PKR-like endoplasmic reticulum kinase) pathway is a key branch of the unfolded protein response (UPR), and is crucial for maintaining cellular homeostasis. In neurodegenerative diseases, fac...

Clinical profile and outcomes of acute ischemic stroke in older persons: A prospective age-group comparative study [2026] - 689KB
by Japleen Kaur, Monika Singla, Harsh Kishore, Gagandeep Singh
Background & Objective: With a global population aging, understanding stroke characteristics in older persons becomes increasingly critical for optimising care strategies. This study investigated clin...

Longitudinal retinal and choroidal microvascular changes in carotid artery stenosis: Comparative outcomes of surgical and medical management using optical coherence tomography angiography [2026] - 571KB
by Hakika Erdoğan, Yusuf Emre Okur, Sedat Özcan, Mustafa Çam
Background & Objective: Carotid artery stenosis (CAS) is a major cause of chronic cerebral hypoperfusion and ischemic stroke. Because retinal circulation originates from the internal carotid artery, o...

Erdun-Ujile plus tirofiban for progressive ischemic stroke: a single-centre retrospective cohort from Inner Mongolia [2026] - 644KB
by Wuyingga Bao, Nu’enjiya Zhao, Yuehui Liu, Xinhong Zhang, Dongwei Zhang, Yang Liu
Background & Objective: Progressive ischaemic stroke (PIS) is associated with early neurological worsening and poor outcome, and optimal acute management remains uncertain. In some centres, tirofiban ...

Multimorbidity and functional motor and balance outcomes post-stroke: A retrospective analysis across all age groups [2026] - 428KB
by Turkadevi Arumugam, Eliza Binti Hafiz, Mazlina Mazlan, Wahida Wahid
Background & Objective: Multimorbidity is defined as the co-existence of two or more chronic conditions, which is common in stroke survivors and may influence their functional recovery. However, its i...

The Needs of Parents Caring for Children with Epilepsy Questionnaire (NPCEQ-TR): Turkish adaptation, validity, and reliability study [2026] - 701KB
by Necla KASIMOĞLU, Muhammet Ali AYDIN, Birgül TUNCAY, Ayşe GÜROL, Abdullah ADIYAMAN
Objectives: This study aimed to translate the Needs of Parents Caring for Children with Epilepsy Questionnaire (NPCEQ) into Turkish (NPCEQ-TR) and evaluate its psychometric properties, including valid...

From tremor to myoclonus associated with valproate: Clinical insights and polymyographic evaluation [2026] - 583KB
by Leyla KÖse Leba, Ayşegul Gündüz, Çiğdem Özkara, Seher Naz Yeni, Şakir Delil, Meral E Kiziltan
Objectives: We aimed to perform clinical and polymyography analyses in patients with epilepsy to assess characteristics of involuntary movements associated with valproate. Method: All consecutive pati...

Reliability of provocative tests in determining the severity of carpal tunnel syndrome [2026] - 466KB
by Pricilla Yani Gunawan, Sylvia Aurora, Reza Stevano, Jeremiah Hilkiah Wijaya
Background & Objectives: Electrodiagnostic study is the most frequently used diagnostic tool in confirming and grading carpal tunnel syndrome (CTS) severity. However, limited availability of electrodi...